RESEARCH AREAS

    Dr. Guangjin Hou received his B.S. degree from the Central China Normal University in 2001. He earned his M.S. degree in 2004 as a joint-cultivated graduate candidate of Huazhong University of Science and Technology & Wuhan Institute of Physics and Mathematics, the Chinese Academy of Scieneces (CAS), and obtained his Ph.D degree in 2007 at Wuhan Institute of Physics and Mathematics, CAS. Dr. Hou worked with Prof. Hans W. Spiess at the Max-Planck Institute for Polymer Research of the Max-Planck Society, Germany, as a postdoctoral researcher from 2007 to 2009. Then he joined Prof. Tatyana Polenova's group in 2009 at the University of Delaware as a postdoctoral researcher, and was promoted to a Research Associate II in 2011. In 2012, Dr. Hou began his independent research career at the University of Delaware as a NMR senior scientist. Since September 2017, he joined the Dalian Institute of Chemical Physics, CAS, as a full Professor of Chemistry, and was appointed as the group leader of Solid-State Nuclear Magnetic Resonance and Catalytic Chemistry in State Key Laboratory of Catalysis. He is an awardee of 2017 National "Thousand Talents" Youth Program.

    His current research interest focuses on the methodology development of solid-state NMR spectroscopy and its applications in the structural and dynamics studies of solid materials. He has published over 50 articles so far in Proc. Natl. Acad. Sci., Nat. Commun., J. Am. Chem. Soc., Acc. Chem. Res., Environ. Sci. Technol. etc, including 1 PNAS and 7 JACS articles as the first author or corresponding author.

Research Interests:

1. Development of Solid-state NMR methodology and applications in structural & dynamics studies of solid materials;

2. Solid-state NMR studies of nano-interfacial multi-functional complex catalytic materials;

3. Atomic-resoluton investigations of catalytic mechanism and dynamics in catalytic reactions of syngas by solid-state NMR;

4. Solid-state NMR studies of sodium-ion-battery (SIB) materials;

5. Structural and dynamics studies of protein assemblies by solid-sate NMR.

 

PROFESSIONAL EXPERIENCE

Professor	Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China	2017-present
Associate Professor	Dalian Institute of Chemical Physics, Chinese Academy of Sciences, Dalian, China	2016-2017
NMR Spectroscopist	Department of Chemistry and Biochemistry University of Delaware, Newark, DE, USA	2012-2017
Research Associate II	Department of Chemistry and Biochemistry University of Delaware, Newark, DE, USA	2011-2012
Postdoctoral Researcher	Department of Chemistry and Biochemistry University of Delaware, Newark, DE, USA Advisor: Prof. Tatyana Polenova	2009-2011
Postdoctoral Researcher	Max-Planck Institute for Polymer Research, Mainz, Germany Advisor: Prof. Hans W. Spiess	2007-2009

 

EDUCATION

 

Ph. D.	Radio Physics Chinese Academy of Sciences, Wuhan, China Advisor: Prof. Feng Deng and Prof. Chaohui Ye	2007
M. Sc.	Condensed Matter Physics Huazhong University of Science and Technology, Wuhan, China Advisor: Prof. Chaohui Ye	2004
B. Sc.	Physics Central China Normal University, Wuhan, China	2001

 

 

HONORS AND AWARDS

“Youth Scholar of Da-Yu Zhang” of Dalian Institute of Chemical Physics, CAS (2017)

“Thousand Youth Talents Plan” of China (2017)

“Hundred Talent Program” of Dalian Institute of Chemical Physics, CAS (2016)

Jack E. Crow Travel Award for Rocky Mountain Conference on Analytical Chemistry (2010)

Postdoctoral Research Stipend of Max-Planck Society (2007-2009)

Outstanding Graduate of the Chinese Academy of Sciences (2007)

 

REPRESENTATIVE PUBLICATIONS

1. H. Zhang*, G. Hou*, M. Lu, J. Ahn, I. Byeon, C. Langmead, J. Perilla, I. Hung, P. Gor'kov, Z. Gan, W. Brey, D. Case, K. Schulten, A. Gronenborn, T. Polenova, HIV-1 capsid function is regulated by dynamics: quantitative atomic-resolution insights by integrating magic-angle spinning NMR, QM/MM, and MD, J. Am. Chem. Soc., 138 (2016), 14066-14075. (*Equal Contribution)

2. M. Lu*, G. Hou*, H. Zhang, C. L. Suiter, J. Ahn, I. L. Byeon, I. Hung, P. Gor'kov, Z. Gan, W. Brey, A. M. Gronenborn, T. Polenova, Dynamic allostery governs cyclophilin A-HIV capsid interplay, Proc. Nat. Acad. Sci. USA, 112 (2015), 14617-14622. (*Equal Contribution)

3. G. Hou, S. Paramasivam, S. Yan, A. J. Vega, T. Polenova, Multidimensional MAS NMR Spectroscopy for Site-Resolved Measurement of Proton Chemical Shift Anisotropy in Biological Solids, J. Am. Chem. Soc., 135 (2013), 1358-1368.

4. Y. Han*, G. Hou*, C. L. Suiter, J. Ahn, In-Ja L. Byeon, A. S. Lipton, S. Burton, I. Hung, P. Gor'kov, Z. Gan, W. Brey, A. M. Gronenborn, T. Polenova, Ultrahigh Resolution Solid-state NMR Reveals an Unstructured or Random Coil Conformation of Spacer Peptide 1 (SP1) in HIV-1 CA-SP1 Tubular Assemblies, J. Am. Chem. Soc., 135 (2013), 17793-17803. (*Equal Contribution)

5. L. Byeon*, G. Hou*, Y. Han, C. L. Suiter, J. Ahn, J. Jung, C. Byeon, A. M. Gronenborn, T. Polenova, Motions on the Millisecond Timescale and Multiple Conformations of HIV-1 Capsid Protein: Implications for Structural Polymorphism of CA Assemblies, J. Am. Chem. Soc., 134 (2012), 6455-6466. (*Equal Contribution)

6. G. Hou, I. L. Byeon, J. Ahn, A. M. Gronenborn, T. Polenova, 1H-13C/1H-15N Heteronuclear Dipolar Recoupling by R-Symmetry Sequences Under Fast Magic Angle Spinning for Dynamics Analysis of Biological and Organic Solids, J. Am. Chem. Soc., 133 (2011), 18646-18655.

7. G. Hou, S. Yan, S. Sun, Y. Han, I. L. Byeon, J. Ahn, J. Concel, A. Samoson, A. M. Gronenborn, T. Polenova, Spin Diffusion Driven by R-Symmetry Sequences: Applications to Homonuclear Correlation Spectroscopy in MAS NMR of Biological and Organic Solids, J. Am. Chem. Soc., 133 (2011), 3943-3953.

8. G. Hou, S. Ding, L. Zhang, F. Deng, Breaking the T1 Constraint for Quantitative Measurement in Magic Angle Spinning Solid-State NMR Spectroscopy, J. Am. Chem. Soc., 132 (2010), 5538-5539.